Second-generation antidepressants.
نویسندگان
چکیده
منابع مشابه
Second-generation antidepressants for depression in adults.
Evidence-Based Answer Second-generation antidepressants (antidepressants other than tricyclics and monoamine oxidase inhibitors) used to treat major depressive disorder in adults have similar effectiveness. However, some clinically significant differences among individual drugs exist with respect to onset of action and adverse effects, which may affect treatment choices. For example, mirtazapin...
متن کاملAntidepressants and antiepileptic drugs for chronic non-cancer pain.
The development of newer classes of antidepressants and second-generation antiepileptic drugs has created unprecedented opportunities for the treatment of chronic pain. These drugs modulate pain transmission by interacting with specific neurotransmitters and ion channels. The actions of antidepressants and antiepileptic drugs differ in neuropathic and non-neuropathic pain, and agents within eac...
متن کاملEfficacy and safety of second-generation antidepressants in the treatment of major depressive disorder.
BACKGROUND Reviews have compared the efficacy and tolerability of newer second-generation antidepressants with those of placebo or older treatments, but comparative evidence for use of second-generation antidepressants to treat major depressive disorder has not been evaluated. PURPOSE To systematically evaluate comparative data on the efficacy, effectiveness, and tolerability of commonly pres...
متن کاملStrategic use of new generation antidepressants for depression, SUN(^_^)D : study design and rationale
Background After more than half a century of modern psychopharmacology, with billions of dollars spent on antidepressants annually world-wide, we lack good evidence to guide our everyday decisions in conducting antidepressant treatment of patients with major depression. First we did not know which antidepressant to use as first line treatment. Second we do not know which dosage we should be aim...
متن کاملComparative benefits and harms of second generation antidepressants and cognitive behavioral therapies in initial treatment of major depressive disorder: systematic review and meta-analysis
STUDY QUESTION What are the benefits and harms of second generation antidepressants and cognitive behavioral therapies (CBTs) in the initial treatment of a current episode of major depressive disorder in adults? METHODS This was a systematic review including qualitative assessment and meta-analyses using random and fixed effects models. Medline, Embase, the Cochrane Library, the Allied and Co...
متن کاملEfficacy of second generation antidepressants in late-life depression: a meta-analysis of the evidence.
OBJECTIVE Second-generation antidepressants are commonly used to treat major depression in late-life. This systematic review and meta-analysis was undertaken to assess the evidence for efficacy of second-generation antidepressants in late-life major depression. METHODS The Cochrane Library (2006 [3]), MEDLINE (1966 to August 2006), and meeting presentations were searched for trials of second-...
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عنوان ژورنال:
- Canadian family physician Medecin de famille canadien
دوره 57 10 شماره
صفحات -
تاریخ انتشار 2011